Multiple plots watchlist

Is it possible to have a script only run once but fill several watchlist columns with different plots instead of running the same script in each column and plotting a different variable? I’m reaching memory limits frequently due to a couple of data intensive codes running in several columns on large lists and trying to make it more efficient. (Yes- I have a LOT of RAM installed)

PS - sorry for all the questions recently. I’m on a project that should be complete ?